An Indian man studying in Melbourne has been missing for six days, prompting concerns for his safety.

Dipakkumar Chaudhari, 22, was last seen headed towards Crown Casino between 5.20am and 6.30am last Thursday.

His Glen Iris housemates reported him missing over the weekend.

Police and housemates have been unable to contact Mr Chaudhari as his mobile diverts immediately to voicemail, suggesting a dead battery or the phone being turned off, police said.

Police have been told that his disappearance is out of character.

Anyone with information about his whereabouts should contact Crime Stoppers on 1800 333 000 or go to www.crimestoppers.com.au