BOB and Sue Neville have a caravan packed and ready in the driveway of their NSW south coast home.

As soon as they hear any news that might lead them to their missing son, they will be on the road.

Bobby Neville, who would now be 33, went missing from their Coledale home on September 30, 2008. He is one of about 35,000 people reported missing in Australia every year.

Missing Persons Week starts today and Mr and Mrs Neville are appealing for public help in tracking down their son.

They believe Bobby, pictured, who suffers from a medical condition, and has worked interstate before, may be working in the bush as a roustabout or handyman.

''If we got news we'd drop everything and go to him,'' Mr Neville said.

Bobby is 183 centimetres tall, with a tan complexion and slim build. At the time of his disappearance he had dark, short wavy hair.

Anyone with information about his disappearance should contact Crime Stoppers on 1800 333 000.